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Aura

MedGen UID:
65921
•Concept ID:
C0236018
•
Finding
Synonym: Auras
SNOMED CT: Observation of aura (18618006); Aura (18618006)

Definition

Sensations experienced immediately prior to the onset of a seizure, migraine headache, or other nervous system disorder symptoms. Also, the patient''s recognition of the beginning of an epileptic attack. Use PARAPSYCHOLOGY or PARAPSYCHOLOGICAL PHENOMENA to access references on psychic auras and halos. [from PSY]

Professional guidelines

PubMed

Rimegepant: A Review in the Acute Treatment and Preventive Treatment of Migraine.
Blair HA
CNS Drugs 2023 Mar;37(3):255-265. Epub 2023 Feb 4 doi: 10.1007/s40263-023-00988-8. PMID: 36739335Free PMC Article
Migraine Aura: Pathophysiology, Mimics, and Treatment Options.
Fraser CL, Hepschke JL, Jenkins B, Prasad S
Semin Neurol 2019 Dec;39(6):739-748. Epub 2019 Dec 17 doi: 10.1055/s-0039-1700525. PMID: 31847045
Migraine and Tension-Type Headache: Diagnosis and Treatment.
Burch R
Med Clin North Am 2019 Mar;103(2):215-233. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.003. PMID: 30704678

Recent clinical studies

Etiology

Migrainous infarction.
Chiang CC, Chen SP
Handb Clin Neurol 2024;199:465-474. doi: 10.1016/B978-0-12-823357-3.00021-5. PMID: 38307663
Migraine with aura.
Lucas C
Rev Neurol (Paris) 2021 Sep;177(7):779-784. Epub 2021 Aug 9 doi: 10.1016/j.neurol.2021.07.010. PMID: 34384631
Genetics of migraine.
Ducros A
Rev Neurol (Paris) 2021 Sep;177(7):801-808. Epub 2021 Jul 23 doi: 10.1016/j.neurol.2021.06.002. PMID: 34304862
Migraine and stroke.
Zhang Y, Parikh A, Qian S
Stroke Vasc Neurol 2017 Sep;2(3):160-167. Epub 2017 May 29 doi: 10.1136/svn-2017-000077. PMID: 28989805Free PMC Article
Hormonal Contraceptives and Migraine With Aura-Is There Still a Risk?
Calhoun AH
Headache 2017 Feb;57(2):184-193. Epub 2016 Oct 24 doi: 10.1111/head.12960. PMID: 27774589

Diagnosis

Hemiplegic migraine.
de Boer I, Hansen JM, Terwindt GM
Handb Clin Neurol 2024;199:353-365. doi: 10.1016/B978-0-12-823357-3.00015-X. PMID: 38307656
Hemiplegic Migraine.
Nandyala A, Shah T, Ailani J
Curr Neurol Neurosci Rep 2023 Jul;23(7):381-387. Epub 2023 May 29 doi: 10.1007/s11910-023-01277-z. PMID: 37247170
Migraine with aura.
Lucas C
Rev Neurol (Paris) 2021 Sep;177(7):779-784. Epub 2021 Aug 9 doi: 10.1016/j.neurol.2021.07.010. PMID: 34384631
Migraine Aura: Updates in Pathophysiology and Management.
Lai J, Dilli E
Curr Neurol Neurosci Rep 2020 May 19;20(6):17. doi: 10.1007/s11910-020-01037-3. PMID: 32430657
Migraine Aura: Pathophysiology, Mimics, and Treatment Options.
Fraser CL, Hepschke JL, Jenkins B, Prasad S
Semin Neurol 2019 Dec;39(6):739-748. Epub 2019 Dec 17 doi: 10.1055/s-0039-1700525. PMID: 31847045

Therapy

Estetrol/Drospirenone: A Review in Oral Contraception.
Lee A, Syed YY
Drugs 2022 Jul;82(10):1117-1125. Epub 2022 Jul 4 doi: 10.1007/s40265-022-01738-8. PMID: 35781795Free PMC Article
Migraine with aura.
Lucas C
Rev Neurol (Paris) 2021 Sep;177(7):779-784. Epub 2021 Aug 9 doi: 10.1016/j.neurol.2021.07.010. PMID: 34384631
Diagnostic and therapeutic aspects of hemiplegic migraine.
Di Stefano V, Rispoli MG, Pellegrino N, Graziosi A, Rotondo E, Napoli C, Pietrobon D, Brighina F, Parisi P
J Neurol Neurosurg Psychiatry 2020 Jul;91(7):764-771. Epub 2020 May 19 doi: 10.1136/jnnp-2020-322850. PMID: 32430436Free PMC Article
Menstrual Migraine and Treatment Options: Review.
Maasumi K, Tepper SJ, Kriegler JS
Headache 2017 Feb;57(2):194-208. Epub 2016 Dec 2 doi: 10.1111/head.12978. PMID: 27910087
Cadasil.
Chabriat H, Joutel A, Dichgans M, Tournier-Lasserve E, Bousser MG
Lancet Neurol 2009 Jul;8(7):643-53. doi: 10.1016/S1474-4422(09)70127-9. PMID: 19539236

Prognosis

Hemiplegic migraine.
de Boer I, Hansen JM, Terwindt GM
Handb Clin Neurol 2024;199:353-365. doi: 10.1016/B978-0-12-823357-3.00015-X. PMID: 38307656
Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP.
Krause DN, Warfvinge K, Haanes KA, Edvinsson L
Nat Rev Neurol 2021 Oct;17(10):621-633. Epub 2021 Sep 20 doi: 10.1038/s41582-021-00544-2. PMID: 34545218
Migraine and stroke.
Zhang Y, Parikh A, Qian S
Stroke Vasc Neurol 2017 Sep;2(3):160-167. Epub 2017 May 29 doi: 10.1136/svn-2017-000077. PMID: 28989805Free PMC Article
Metastatic disease from uveal melanoma: treatment options and future prospects.
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article
The triggers or precipitants of the acute migraine attack.
Kelman L
Cephalalgia 2007 May;27(5):394-402. Epub 2007 Mar 30 doi: 10.1111/j.1468-2982.2007.01303.x. PMID: 17403039

Clinical prediction guides

Hemiplegic migraine.
de Boer I, Hansen JM, Terwindt GM
Handb Clin Neurol 2024;199:353-365. doi: 10.1016/B978-0-12-823357-3.00015-X. PMID: 38307656
Migralepsy, what it is and what it is not.
Vercueil L
Rev Neurol (Paris) 2022 Sep;178(7):654-658. Epub 2022 Feb 9 doi: 10.1016/j.neurol.2022.01.006. PMID: 35148906
Neuroimaging clues of migraine aura.
Hadjikhani N, Vincent M
J Headache Pain 2019 Apr 3;20(1):32. doi: 10.1186/s10194-019-0983-2. PMID: 30943894Free PMC Article
Psoriasis and migraine.
Capo A, Affaitati G, Giamberardino MA, Amerio P
J Eur Acad Dermatol Venereol 2018 Jan;32(1):57-61. Epub 2017 Aug 2 doi: 10.1111/jdv.14472. PMID: 28707753
Vision and migraine.
Vincent MB
Headache 2015 Apr;55(4):595-9. Epub 2015 Mar 11 doi: 10.1111/head.12531. PMID: 25758366

Recent systematic reviews

Impact of influenza, herpes zoster, and pneumococcal vaccinations on the incidence of cardiovascular events in subjects aged over 65 years: a systematic review.
Addario A, Célarier T, Bongue B, Barth N, Gavazzi G, Botelho-Nevers E
Geroscience 2023 Dec;45(6):3419-3447. Epub 2023 Jun 3 doi: 10.1007/s11357-023-00807-4. PMID: 37269492Free PMC Article
Primary headache epidemiology in children and adolescents: a systematic review and meta-analysis.
Onofri A, Pensato U, Rosignoli C, Wells-Gatnik W, Stanyer E, Ornello R, Chen HZ, De Santis F, Torrente A, Mikulenka P, Monte G, Marschollek K, Waliszewska-Prosół M, Wiels W, Boucherie DM, Onan D, Farham F, Al-Hassany L, Sacco S; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2023 Feb 14;24(1):8. doi: 10.1186/s10194-023-01541-0. PMID: 36782182Free PMC Article
Imaging the inflammatory phenotype in migraine.
Christensen RH, Gollion C, Amin FM, Moskowitz MA, Hadjikhani N, Ashina M
J Headache Pain 2022 Jun 1;23(1):60. doi: 10.1186/s10194-022-01430-y. PMID: 35650524Free PMC Article
Clinical features of visual migraine aura: a systematic review.
Viana M, Tronvik EA, Do TP, Zecca C, Hougaard A
J Headache Pain 2019 May 30;20(1):64. doi: 10.1186/s10194-019-1008-x. PMID: 31146673Free PMC Article
Acupuncture for the prevention of episodic migraine.
Linde K, Allais G, Brinkhaus B, Fei Y, Mehring M, Vertosick EA, Vickers A, White AR
Cochrane Database Syst Rev 2016 Jun 28;2016(6):CD001218. doi: 10.1002/14651858.CD001218.pub3. PMID: 27351677Free PMC Article

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